Use of Di(2-ethylhexyl) Phthalate–Containing Medical Products and Urinary Levels of Mono(2-ethylhexyl) Phthalate in Neonatal Intensive Care Unit Infants

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Use of Di(2-ethylhexyl) Phthalate–Containing Medical Products and Urinary Levels of Mono(2-ethylhexyl) Phthalate in Neonatal Intensive Care Unit Infants

OBJECTIVE Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer used in medical products made with polyvinyl chloride (PVC) plastic and may be toxic to humans. DEHP is lipophilic and binds noncovalently to PVC, allowing it to leach from these products. Medical devices containing DEHP are used extensively in neonatal intensive care units (NICUs). Among neonates in NICUs, we studied exposure to DEHP...

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Exposure to di-(2-ethylhexyl) phthalate among premature neonates in a neonatal intensive care unit.

OBJECTIVE Premature neonates who spend time in a neonatal intensive care unit may be at increased risk of adverse health effects from exposure to di-(2-ethylhexyl) phthalate (DEHP) because of their increased risk of high exposure, their small body size, and their physical condition. DEHP, a reproductive toxicant in animals, is a major component in polyvinyl chloride (PVC) plastics, which are fr...

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Evaluation of Maternal Anxiety in Mothers of Infants Admitted to the Neonatal Intensive Care Unit

Background: Preterm birth and subsequent admission of the infant to neonatal intensive care unit (NICU) can be distressing for parents and lead to their anxiety. The aim of this study was to evaluate maternal anxiety in mothers of infants admitted to the NICU and determine the characteristics associated with maternal anxiety....

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Adsorption of Bis (2-ethylhexyl) Phthalate

The adsorption of Bis (2-ethylhexyl) phthalate (DEHP) on the carbon adsorbents (Chezacarb S and Chezacarb SH) and polymer adsorbent on basis of polypropylene with polyethylene (Reo Fb) was studied. Efficiency of DEHP adsorption (concentration DEHP to 10 g.L, concentration of the adsorbents 1.7 g.L) was more then 99.9 %. By the sample from groundwater was efficiency more as 99.7 % in the case of...

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The in vitro serum protein-binding characteristics of bis-(2-ethylhexyl) phthalate and its principal metabolite, mono-(2-ethylhexyl) phthalate.

The metabolism and toxicity of the ubiquitous plasticizer, bis-(2-ethylhexyl) phthalate (DEHP), and its principal metabolite, mono-(2-ethylhexyl) phthalate (MEHP), have been extensively investigated. In an attempt to understand their disposition in man, we studied the in vitro serum protein-binding characteristics of these compounds, using ultracentrifugation and agarose gel electrophoresis. Th...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 2005

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.7932